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Gastro-enteritis - Cryptosporidium species

Advices

1 months - 18 years

Indications: Immuuncompetent

Priority Medication Remarks
Priority:
1st choice
Medication:

Remarks:

niet behandelen, tenzij langdurige klachten

Priority:
2nd choice
Medication:

Remarks:

nitazoxanide po gedurende 3 dagen: 1-3 jaar: 2 dd 100 mg, 4-11 jaar: 2 dd 200 mg, > 11 jaar: 2 dd 500 mg

1 months - 18 years

Indications: Immuungecompromitteerd

Priority Medication Remarks
Priority:
1st choice
Remarks:

Meest effectieve therapie is herstel van eigen afweer (bv door HAART bij HIV of verminderen immuunsuppressie)

Priority:
2nd choice
Remarks:

nitazoxanide po gedurende 14-28 dagen: 1-3 jaar: 2 dd 100 mg, 4-11 jaar: 2 dd 200 mg, > 11 jaar: 2 dd 500 mg

Priority:
2nd choice alternative
Medication:

paromomycine po 14 days

+

azitromycine po 10mg/kg 1dd 14 days

Remarks:

Behandelduur eventueel verlengen tot 28 dagen.

Dosis paromomycine: https://www.kinderformularium.nl/geneesmiddel/25/paromomycine.

Dosis azitromycine: https://www.kinderformularium.nl/geneesmiddel/309/azitromycine.

Sources

  1. Pubmed.gov publication # 19632225

    Rossignol JF (2010) Cryptosporidium and Giardia: treatment options and prospects for new drugs. Exp Parasitol. 124:45-53.

  2. Pubmed.gov publication # 20689422

    Cabada MM, White AC Jr. (2010) Treatment of cryptosporidiosis: do we know what we think we know? Curr Opin Infect Dis. 23(5):494-9.

  3. Pubmed.gov publication # 19400754

    Pantenburg B, Cabada MM, White AC jr. (2009) Treatment of cryptosporidiosis. Expert Rev Anti Infect Ther 7: 385-91

  4. Pubmed.gov publication # 17335543

    Abubakar I, Aliyu SH, Arumugam C, Usman NK, Hunter PR (2007) Treatment of cryptosporidiosis in immunocompromised individuals: systematic review and meta-analysis. Br J Clin Pharmacol. 63:387-93.

  5. SWAB Guideline IX - Acute infectieuze diarree
Antimicrobial resources

The following antimicrobial agents have been used in these recommendations:

  • paromomycine
  • azitromycine
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Metadata

Swab vid: G-390667.2
Updated: 03/26/2021 - 11:32
Status: Published