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CF: Eradicatie van Pseudomonas aeruginosa

Advices

1 months - 18 years
Priority Medication Remarks
Priority:
1st choice
Medication:

ciprofloxacine po 40mg/kg/24h 2dd 21 days

+

tobramycine inhalation 300mg 2dd 28 days

Remarks:

Ciprofloxacine: max. 2 gram/24u.

Tobramycine: vernevelen.

Priority:
1st choice alternative
Medication:

ciprofloxacine po 40mg/kg/24h 2dd 21 days

+

colistine inhalation 2million. IU 2dd 3 months

Remarks:

Ciprofloxacine: max. 2 gram/24u.

Colistine: vernevelen.

Priority:
2nd choice
Medication:

ceftazidim iv

+

tobramycine iv

Remarks:

1e keuze in geval van ziek: tekenen van tachy-/dyspnoe +/- toegenomen zuurstofbehoefte

Ceftazidim: 200 mg/kg/24u continu iv (max. 12 gram/24u); Alternatief intermitterende toediening: 200 mg/kg/24u in 4dd iv (max. 12 gram/24u) 

Tobramycine: 10-15 mg/kg/24u in 1dd iv (definitieve dosering op geleide van Therapeutic drug monitoring (TDM))

Sources

Antimicrobial resources

The following antimicrobial agents have been used in these recommendations:

  • ciprofloxacine
  • tobramycine
  • colistine
  • ceftazidim
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Metadata

Swab vid: G-390803.1
Updated: 06/24/2022 - 14:30
Status: Published